Newborn screening programmes began in the 1960s, have traditionally been conducted without parental permission and have grown dramatically in the last decade. Whether these programmes serve patients’ best interests has recently become a point of controversy. Privacy advocates, concerned that newborn screening infringes upon individual liberties, are demanding fundamental changes to these programmes. These include parental permission and limiting the research on the blood samples obtained, an agenda at odds with the viewpoints of newborn screening advocates. This essay presents the (...) history of newborn screening in the USA, with attention to factors that have contributed to concerns about these programmes. The essay suggests that the rapid increase in the number of disorders screened for and the addition of research without either public knowledge or informed consent were critical to the development of resistance to mandatory newborn screening and research. Future newborn screening initiatives should include public education and comment to ensure continued support. (shrink)

This chapter contains sections titled: Modal Logic, Intension, and Meaning Knowledge, the Given, and the a priori Values and Morality.

The theoretical and practical problems of providing incentives for people's activity in society are becoming increasingly more urgent as the role of the human factor in the development of society grows. In light of modern historical experience, we can see the onesidedness of conceptions according to which the types and directions of activity are mechanically predetermined by conditions external to it, and we can see the necessity of understanding the laws of activity itself in all their complicated dialectical essence. These (...) problems have become particularly important at the present stage of development of Soviet society, when a greater active involvement of the masses and profound changes in social psychology are becoming acutely necessary. (shrink)

Our ultimate purpose is to give an axiomatic treatment of recursion theory sufficient to develop the priority method. The direct or abstract approach is to keep in mind as clearly as possible the methods actually used in recursion theory, and then to formulate them explicitly. The indirect or experimental approach is to look first for other mathematical theories which seem similar to recursion theory, to formulate the analogies precisely, and then to search for an axiomatic treatment which covers not only (...) recursion theory but also the analogous theories as particular cases.The first approach is more general because it does not depend on the existence of analogues. A concrete mathematical theory, it seems, need have no such analogues and still be important, as e.g. classical number theory. In such a case, an axiomatic treatment may still be useful for exhibiting the mathematical structure of the theory considered and the assumptions on which it rests. However, it will lack one of the most heavily advertised advantages of the axiomatic method, namely, the “economy of thought” which results from an uniform theory for several different and interesting cases: we cannot hope for this if, by hypothesis, we know of only one particular case. In contrast, the second approach, if successful at all, is bound to achieve such “economy” because we start out with several interesting particular cases. Another possible virtue of the second approach is that of field work over insight: the abstract pattern that we are looking for and hoping to formalize in axioms, may not be evident in any one mathematical theory, but may spring to the eye if one happens to look simultaneously at several theories which happen to realize the pattern. (shrink)

For T any completion of Peano Arithmetic and for n any positive integer, there is a model of T of size $\beth_n$ with no (n + 1)-length sequence of indiscernibles. Hence the Hanf number for omitting types over T, H(T), is at least $\beth_\omega$ . (Now, using an upper bound previously obtained by Julia Knight H (true arithmetic) is exactly $\beth_\omega$ ). If T ≠ true arithmetic, then $H(T) = \beth_{\omega1}$ . If $\delta \not\rightarrow (\rho)^{ , then any completion of (...) Peano Arithmetic has a model of size δ with no set of indiscernibles of size ρ. There are similar results for theories strongly resembling Peano Arithmetic, e.g., ZF + V = L. (shrink)

Social inequalities in health in the UK persist despite attempts to reduce them. We argue that work and pensions constitutes an area of intervention where there is potential to make change happen. We propose that workers who are exposed to significant health risks through their occupation should be allowed to draw their state pension earlier, based on a minimum number of years in the workforce. We model this proposal on similar policies in other European countries. In our modification, the pension (...) age and the retirement age would be separated, such that workers can receive a state pension whether or not they choose to continue working. This arrangement may encourage workers either to reduce their working hours or to change to less demanding or harmful work. The health of these workers would thereby benefit from reduced exposure to a harmful work environment, reduced stress and more opportunities for rest and relaxation. However, it has also been suggested that retirement is bad for mental health. In response, our proposal enables workers to phase in full retirement over a period of part-time work, and we believe that this would counter any potential negative effects on health caused by retirement. (shrink)

Two different models for chemical bond were developed almost simultaneously after the Schrödinger formulation of quantum theory. These are known as the valence bond (VB) and molecular orbital (MO) theories. Initially chemists preferred the VB theory and ignored the MO theory. Now the VB theory is almost dropped out of currency. The context of discovery and Linus Pauling’s overpowering influence gave the VB theory its initial advantage. The current universal acceptance of the MO theory is due to its ability to (...) provide direct interpretation of many different types of experiments now being pursued. In current research both localized bonds and delocalized charge distributions play important roles and the MO theory has been successful in giving a good account of both. (shrink)

system reflected in Saussure's linguistic theory, and so influential in the great progress linguistic theory has made in this century. Indeed, Granger sees linguistic theory as expressing a paradigm for scientific theorizing, which research in other social sciences should adopt. But 'structuralism' as a method in science does not, in Granger's view, begin with Saussure and the linguists. It is nothing less than the strategy of all the sciences, both natural and social, since their beginnings. Now, 'structuralism' is a 'trendy' (...) term no less in Anglophone methodology than in Francophone philosophy. But Granger's employment of the term is not to be assimilated to this trend, nor to the fashionable excesses for which this expression has been a watch word (he explicitly separates himself from this movement in the preface to the second edition). The exact nature of what Granger calls 'structuralist' methods is the subject of a large part of this work, and I will not dwell on it much further in this introduction. Suffice it to say that Granger's demand for structuralist description is nothing less than the recognition that the successful pursuit of science requires that its terms and predicates pick out what we may call 'natural kinds'; that is, describe classes of items that bear uniform nomolog ical relations to one another. A science whose descriptive terms do not meet this condition will never produce any laws that reflect such nomological connections. (shrink)

G. E. M. Anscombe; I *—The Presidential Address: Existence and Truth, Proceedings of the Aristotelian Society, Volume 88, Issue 1, 1 June 1988, Pages 1–12, http.

I propose three new curved spacetime versions of the Dirac Equation. These equations have been developed mainly to try and account in a natural way for the observed anomalous gyromagnetic ratio of Fermions. The derived equations suggest that particles including the Electron which is thought to be a point particle do have a finite spatial size which is the reason for the observed anomalous gyromagnetic ratio. A serendipitous result of the theory, is that, to of the equation exhibits an asymmetry (...) in their positive and negative energy solutions the first suggestion of which is clear that a solution to the problem as to why the Electron and Moun—despite their acute similarities—exhibit an asymmetry in their mass is possible. The Moun is often thought as an Electron in a higher energy state. Another of the consequences of three equations emanating from the asymmetric serendipity of the energy solutions of two of these equations, is that, an explanation as to why Leptons exhibit a three stage mass hierarchy is possible. (shrink)

Theoretical philosophy is a term that requires the most meticulous clarification, above all as a subject.

These excerpts have been kindly provided by Professor George L. Kline, who had edited and introduced the English translation of Germenevtika i ee problemy, done from a manuscript by the late Erika Freiberger. The Russian manuscript written in 1918 had been published in installments in the yearbook Kontekst in 1989-92. The excerpts presented here can be found in the 1991 and 1992 issues, in which the installments were edited by Shpet's granddaughter Elena V. Pasternak. The English translation of the entire (...) book is forthcoming. (shrink)

The meaning of the once widely used term the Gibbs Free Energy in terms of available work energy is perfectly illustrated for chemical reactions by the Van’t Hoff Equilibrium Box. Combining this with DeDonder’s extent of reaction variable and using the reaction of $$\hbox {NH}_3$$ to $$\hbox {H}_2$$ and $$\hbox {N}_2$$ at $$200^{\circ }\hbox {C}$$ as an example shows the difference between total work energy and available work energy, and in addition allows calculation of the equilibrium composition, demonstration of the (...) minimum in the Gibbs energy curve, and the standard relationship between $$\Delta _\textrm{r}G^{\circ }$$ and $$\ln {K}$$. (shrink)

(1996). The notion of citizenship in France and its redefinition. The European Legacy: Vol. 1, Fourth International Conference of the International Society for the study of European Ideas, pp. 575-579.